Saturday, August 29, 2020

August 29, 2020, Email to the FDA and the NIH National Library of Medicine Re: Immediate Revision of PubChem Documents Equating Glucose (Blood Sugar) with Dextrose (Corn Sugar)

Numerous online publications erroneously claim that glucose (blood sugar) and dextrose (corn sugar) [1] are identical (or nearly identical), thereby endangering the lives of corn-allergic consumers and patients. [2-7]  The molecular weights of the following two compounds are not identical.  Therefore, which one of these molecular formulas represents straight blood sugar (glucose): the "main sugar that the body manufactures [and] serves as the major source of energy for living cells?” [8] It is clear that the definition of glucose (blood sugar) by Dr. William C. Shiel, Jr. supports the fact that glucose (blood sugar) cannot be equated with corn sugar manufactured from cornstarch (dextrose), since our body does not manufacture corn sugar (dextrose).

Re: PubChem CID 79025, alpha-D-Glucose

The Molecular Formula, C6H12O6, is a corn sugar (dextrose) formulation; and has a Molecular Weight of 180.16 g/mol.

Re: PubChem CID 66370, Dextrose

The Molecular Formula, C6H14O7, is also a corn sugar (dextrose) formulation; and has a Molecular Weight of 198.17 g/mol.

Why is this Determination Critical?

In our corn allergy support groups of over 12K members, personal testimonies reveal that the majority of medical professionals are not aware that dextrose is corn sugar manufactured from cornstarch which can prove fatal to anyone with an IgE-mediated allergy to corn.  It is for this reason that intravenous fluids to which corn sugar (dextrose) has been added are contraindicated for administration to corn-allergic patients. [9] These medical professionals are erroneously equating glucose (blood sugar) with dextrose (corn sugar), thereby endangering the lives of corn-allergic patients.

One physician actually told a corn-allergic patient that “No one can be allergic to dextrose,” and proceeded to administer corn sugar (dextrose) IV fluid to this patient in direct violation of the contraindication warning in the package insert, which resulted in a severe allergic reaction requiring emergency intervention.  As a result of this testimony, and many other similar reports by our members, it took me three years to forward corn allergy documentation to the majority of our nation’s hospitals, colleges of medicine, and colleges of pharmacy.

Even after this monumental effort for the safety of corn-allergic patients, it is apparent that the majority of medical professionals remain oblivious to the danger of corn sugar (dextrose) for patients with an IgE-mediated allergy to corn.  Only recently, it was reported that a physician told a corn-allergic patient that “No one can be allergic to dextrose, since dextrose is naturally present in our bodies.”  He then administered the dextrose-containing IV fluid to this patient resulting in an anaphylactic reaction requiring emergency intervention.

Conclusion:

The contention that glucose (blood sugar) and dextrose (corn sugar) are “identical” is a false narrative which appears to have been initiated by the corn industry decades ago; [10] and endangers the lives of corn-allergic patients and consumers; e.g., some food manufacturers claim their products are corn free even though the product contains dextrose (corn sugar).

Immediate Revision is Required:

This false narrative may never have been revealed without Facebook, which provides a platform for addressing specific and non-specific IgE-mediated allergies through allergy support groups; e.g., these allergy support groups have revealed that, based on membership, corn allergies are more than twice as prevalent as sesame seed allergies. 

Now that this false narrative has been exposed, we are demanding that the NIH National Library of Medicine issue an immediate revision clarifying that these two distinct forms of sugar (one natural; one manufactured from cornstarch) are not identical. [11]

This critical correction will undoubtedly result in the required revision of many published papers; however, protecting the lives of corn-allergic consumers and patients should be your top priority.

Thank you for your immediate attention to this critical concern. 

Diane H., Corn Allergy Advocate
Corn Allergy Advocacy/Resources
Twitter:  @CornAllergy911


References:

[1] CORN SUGAR (DEXTROSE), CODE OF FEDERAL REGULATION 21CFR184.1857

[2] "D-glucose is often referred to as Dextrose or Dextro, they are one and the same and are biochemically identical to the glucose are bodies need."

[3] "Glucose is the sugar in blood, and dextrose is the name given to glucose produced from corn. Biochemically they are identical."

[4] "Glucose and dextrose are almost the same (emphasis added). But these terms are different when considering their chemical structures; glucose molecules can be found in both D-glucose form and L-glucose form but, the term dextrose is used only for D-glucose molecules. Thus, the main difference between glucose and dextrose is that glucose includes both D-form and L-form whereas dextrose includes only the D-form of glucose.” (emphasis added)

[5] "Overall, although both has the same chemical formula (emphasis added) and are simple monosaccharides (sugars) glucose and dextrose still differ . . .” (emphasis added)

[6] "Glucose and Dextrose are biochemically identical."

[7] "Dextrose (chemically identical to glucose) . . ."

[8] William C. Shiel, Jr., MD, FACP, FACR, Medical Definition of Glucose, MedicineNet

[9] CORN SUGAR (DEXTROSE) IV FLUIDS CONTRAINDICATED FOR CORN-ALLERGIC PATIENTS

[10] “Dextrose: All-American Corn Sugar,” Candy Professor, September 29, 2010

[11] Dextrose: Facts vs. Fiction


Additional References

My August 29, 2020, Email to the National Library of Medicine Re: Depositor-Supplied Synonyms in PubChem Documents; e.g., Grape Sugar

My July 2, 2020, Appeal to the NIH National Library of Medicine Re: PubChem CID 79025, Glucose (Blood Sugar) vs. Dextrose (Corn Sugar Derived from Cornstarch)

Corn Allergy: A Potentially Life-Threatening Diagnosis

July, 2020, Month-End Corn Allergy Statistics: 949.9% Increase in 85 Months
(Corn is ubiquitous and is EXEMPT from FDA labeling requirements, resulting in underreporting and suppression of corn allergy statistics).

Corn Allergy References, Surveys, Studies, Statistics, & Petitions
(Includes my submission to The Joint Commission, Congress, FDA, & U.S. Dept. of Health requesting emergency mandate that hospitals stock corn-free foods, liquids, & drugs.)




Blog Post Reference:

August 29, 2020, Email to the FDA and the NIH National Library of Medicine Re: Immediate Revision of PubChem Documents Equating Glucose (Blood Sugar) with Dextrose (Corn Sugar)


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